Anthocyanin-rich black elderberry extract improves markers of HDL function and reduces aortic cholesterol in hyperlipidemic mice

Food and Function (2015)

  • This study used a mouse model of hyperlipidemia to examine the impact of elderberry supplementation in diet.
  • Elderberry supplement was made by Artemis International.
  • They found that AST and fasting glucose levels were reduced, as was CCL2 (cytokine) levels.
  • Total cholesterol in the aorta was also reduced and there was less atherosclerosis progression.
  • The authors concluded that the impact of elderberry on HDL cholesterol levels might be through its affect on gene expression.
  • The dosage with an effect was determined to be 200 mg / kg body weight, which translates to ~75 g for a 70 kg (154 lb) person.

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