The Cytotoxicity of Elderberry Ribosome-Inactivating Proteins Is Not Solely Determined by Their Protein Translation Inhibition Activity
PLoS One (2015)
- Source of S. nigra was not mentioned in the article.
- Observed potential anti-carcinogenic effects due to ribosome inactivating proteins contained in elderberry why do scientists use ‘potential’? [CS1]
- S. nigra proteins induced autophagy (removal of unnecessary or dysfunctional parts of cell (autophagy)). The lectin chain induces these cell death pathways. due to ribosomes? Or something else?
- Potential slight toxicity due to elderberry (ribosome-inactivating proteins[CS2] ) cyanogenic glycosides?
- Observed inhibition of protein synthesis. This suggests that elderberry could prevent the virus from making more of itself and thus infecting more human cells.
Keywords: immunology, function, cytotoxicity