Effects of elderberry juice on fasting and postprandial serum lipids and low-density lipoprotein oxidation in healthy volunteers: a randomized, double-blind, placebo-controlled study.

European Journal of Clinical Nutrition (2004).

https://pubmed.ncbi.nlm.nih.gov/14749743/

  • This was a randomized control trial.
  • Capsules with the equivalent of 5 ml elderberry were given daily over 2 weeks, compared to placebo. There were 17 individuals per group.  A substudy compared to a single dose of 50 ml (only 6 individuals in this substudy).
  • There was a small change in LDL levels in individuals in the treatment group, but it did not attain statistical significance.
  • This suggests a minor effect on serum lipid levels.
  • They observed no change in the high dose treatment but this likely due to small sample size.
  • The paper says a power analysis was conducted, but the assumptions must not have been valid, because only 17 individuals per group is really too small to see an effect in a human study.

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