Pilot clinical study on a proprietary elderberry extract: Efficacy in ad-dressing influenza symptoms

Online J Pharmacol Pharmacokinetics, (2009)


The pdf link at the webpage above was not accessible, but I found a objective-sounding summary here: https://www.herbalgram.org/resources/herbalgram/issues/85/table-of-contents/article3481/  (because full article was unavailable, unable to assess strengths and limitations of analysis and study design)

  •   Randomized clinical trial (RCT) examining the effect of elderberry vs. placebo lozenges in reducing influenza symptoms.
  •   N=32
  •   In subjects taking elderberry, in comparison to their symptoms at baseline, there was a statistically significant reduction in headache, nasal congestion, and fever after 48 hours.
  •   Subjects taking placebo actually showed a worsening in nasal congestion and headache after 48 hours. 
  •   All subjects taking elderberry eventually had no fever
  •   While there was no statistically significant reduction in cough compared to baseline in elderberry or placebo, the severity of cough in subjects taking elderberry was statistically lower compared to placebo.
  •   No adverse effects seen.

Keywords: RCT, influenza, symptom improvement

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